IndraLab
Statements
sparser
"To determine whether the putative TRE2 in the first exon of the Ski gene can render TR/RXR-mediated T3 regulation of the promoter, we generated Ski promoter constructs containing either the wild type TRE2 (Ski-TRE2) or its mutant version (Ski-mTRE2), respectively, to drive firefly luciferase gene expression ( xref ) and evaluated T3-regulation of their activities in Xenopus oocytes ( xref )."
sparser
"As shown in xref , the Ski-TRE2 promoter did not respond to T3 treatment in oocytes preinjected with GFP mRNA, but was strongly activated by T3 in oocytes preinjected with a mixture of TR/RXR mRNAs, suggesting that TRE2 mediated T3 induction through the binding of the TRE to TR/RXR."