IndraLab

Statements

Anthra[1,9-cd]pyrazol-6(2H)-one inhibits IRF3. 2 / 3

| 2

reach

"Interestingly, constitutive active IRF3 (5D) can be inhibited by SP600125; JNK1 can synergize the action of IRF3 (5D), but not the S173A-IRF3 (5D) mutant."

19153595

➶

reach

"The selective JNK inhibitor SP600125 also blocked IRF3 dimerization, suggesting that this function requires JNK (XREF_FIG)."

18713996

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Anthra[1,9-cd]pyrazol-6(2H)-one inhibits IRF3. 2 / 3

INDRA sources:

Databases

Reading