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OTUD4 activates specific deubiquitinase. 2 / 2

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"For instance, the phosphorylation of OTUD4 by casein kinase II activates its K63-specific deubiquitinase activity, which suppresses MyD88-dependent inflammatory signaling [ 32 ]."

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"Here, we demonstrate that the deubiquitinase OTUD4, which nominally encodes a K48 specific deubiquitinase, is phosphorylated near its catalytic domain, activating a latent K63 specific deubiquitinase."

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IndraLab

Statements

OTUD4 activates specific deubiquitinase. 2 / 2

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