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Reactive oxygen species inhibits IRF3. 1 / 1
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"Manassantin B extracted from Saururus chinensis also inhibits the viral protein and RNA levels through stimulating the IFN genes/TANK-binding kinase-1/IFN regulatory factor 3 (IRF3) pathway, increased the production of mitochondrial reactive oxygen species in vitro, and decreases systemic inflammation in mice (Song et al., 2019)."