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Reactive oxygen species inhibits IRF3. 2 / 2

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"SOD2 deficiency mediated ROS accumulation potently inhibits RIG-I-like receptor (RLR)-induced innate immune responses through the regulation of nuclear factor-kappa B (NF-kappaB) and interferon regulatory factor-3 activation."

28574756

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"ROS suppressed the activation of STING, as well as the activation of TBK1 and IRF3, thus leading to reduced IFNbeta transcription."

32886065

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IndraLab

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Reactive oxygen species inhibits IRF3. 2 / 2

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