IndraLab

Statements



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"USP3 promotes clear cell renal cell carcinoma progression by stabilizing MYC and enhancing glycolysis."

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"Glycolysis in GBC cells ws promoted by the USP3 overexpression and inhibited bye USP3 downregulation."

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"It promotes cell proliferation, invasion, migration, DNA damage repair, and glycolysis, potentially via the Wnt/β-catenin signaling pathway.14 Similarly, USP3 promotes cholangiocarcinoma proliferation and invasion through the Wnt/MYC pathway, enhancing tumor cell glycolysis, energy production, and upregulating metabolic target genes such as GLUT1, HK2, PDM2, and LDHA.87 Egfr/Stat3."

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"Among them, SIRT3 exerts anti-cancer effects by inhibiting the Warburg effect, while FGFR2 fusion, FEN1, and USP3 promote aerobic glycolysis through the activation of NF-κB and Wnt pathways."