IndraLab
Statements
sparser
"Treatment was given on predetermined days, in which the prepared matrix scaffolds were used as substrates for impregnation of AgNPs. xref The process includes the exposure of various synthesized scaffolds ( i.e. , CAM alone, uncapped-CAM, capped = TSC-CAM, PVP-CAM and PVA-CAM, SBD-CAM) which were allowed to react on alternate days with the wound area in order to initiate the inflammatory phase followed by the other phases."
sparser
"At the same time, excision wounds treated with uncapped-CAM after the 14 th day showed the presence of a minimal amount of collagen with regeneration and incomplete tissue regeneration, compared with CAM alone, PVA-CAM, PVP-CAM, TSC-CAM or SBD-CAM, as shown in the xref , xref and xref ."
sparser
"From xref , it is proven that the percentage wound contraction for uncapped-CAM was significantly lower than the values for SBD-CAM, TSC-CAM, PVP-CAM and PVA-CAM on all the respective (3 rd , 6 th , 9 th , 14 th and 20 th ) days, which may be due to the absence of surface coating or capping agents in the uncapped-CAM, which are responsible for nanoparticle stability and healing potential."
sparser
"Histopathological analyses of the excision wound models in the control group (without treatment), CAM alone, uncapped-CAM, SBD-CAM, TSC-CAM, PVP-CAM and PVA-CAM on the 9 th and 14 th day after the excision wound injury are depicted using H & E and MT staining in xref , xref and xref ."
sparser
"Histopathological studies on treatment with PVA-CAM in the excision wound model showed a maximum amount of fibroblast presence and collagen regeneration after the 9 th day of the healing process, which was found to be comparatively more effective than CAM alone, uncapped-CAM, PVP-CAM, TSC-CAM or SBD-CAM that showed a minimal amount of fibroblast and collagen regeneration, with the presence of dense inflammation."
sparser
"Finally, PVA-AgNPs, PVP-AgNPs, TSC-AgNPs, uncapped-AgNPs and SBD-suspensions were incorporated into the formulated polymeric matrix to form PVA-AgNP impregnated CAM (PVA-CAM), PVP-AgNP impregnated CAM (PVP-CAM), TSC-AgNP impregnated CAM (TSC-CAM), uncapped-AgNP impregnated CAM (uncapped-CAM) and SBD-suspension impregnated CAM (SBD-CAM), respectively, and freeze dried for further analysis."
sparser
"Wound treatment with uncapped-CAM after the 9 th day of observation showed skin tissue with dense inflammation, an absence of fibroblast development and a very minimal amount of collagen regeneration, and was found to be comparatively less effective than CAM alone, PVA-CAM, PVP-CAM, TSC-CAM or SBD-CAM."
sparser
"Although the percentage wound contraction for PVP-CAM, TSC-CAM and SBD-CAM was quite a bit higher than for uncapped-CAM and the control group, wounds treated with PVA-CAM show the maximum significant wound contraction ( p ≤ 0.001) efficiency due to their biocompatibility with wound tissue."
sparser
"Similarly on the 14 th day after excision wound injury, treatment with PVA-CAM showed an equal maximum regeneration of fibroblast and collagen and was significantly more effective and angiogenic compared with CAM alone, uncapped-CAM, PVP-CAM, TSC-CAM or SBD-CAM that showed a moderate amount of collagen and fibroblast regeneration, with scant inflammation during their healing process."