IndraLab

Statements

KCNA1 activates Kv1.1 channel. 2 / 2

| 2

➶

reach

"Dominant negative mutation p.Arg324Thr in KCNA1 impairs Kv1.1 channel function in episodic ataxia."

27477325

➶

reach

"KCNA1 disease causing mutations have been reported to reduce channel activity by decreasing the number of active channels in the plasma membrane or by impairing the voltage dependent gating and kinetics of the Kv1.1 channel or both [XREF_BIBR, XREF_BIBR]."

33466780

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

KCNA1 activates Kv1.1 channel. 2 / 2

INDRA sources:

Databases

Reading