IndraLab

Statements


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"Consistent with previous studies on AD, the binding of Aldh2, Pecam1, Lrp1, Fn1, Spp1, and IL6 to H3.3 ware significantly increased [ 41 , 42 , 43 ]."

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"Thus, considering our previous study established a role for Hsp90 in FN matrix dynamics, and that both FN and Hsp90 interact with LRP1, we hypothesised that the LRP1 receptor was involved in the turnover of FN in response to Hsp90 inhibition by NOV.."

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"As both Hsp90 and FN interact with LRP1, and the Hs578T cell line expresses LRP1, we hypothesised that this receptor may be involved in Hsp90 mediated FN turnover."