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Bortezomib inhibits OTUD6B. 1 / 1

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"By contrast, we speculate that OTUD6B inhibition outweighs the net effect of bortezomib treatment on LIN28B under clinically achievable bortezomib levels and that this effect adds to the general proteotoxic stress induced by bortezomib in order to explain the observed synergy of OTUD6B inhibition and proteasomal inhibition.Unbiased screening identified OTUD6B as a vulnerability in MM."

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IndraLab

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Bortezomib inhibits OTUD6B. 1 / 1

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