IndraLab

Statements

AICA ribonucleotide inhibits NLRP3. 3 / 3

| 3

➶

reach

"Salicylate and AICAR reduced NLRP3 and cleaved caspase-1 expression, and then decreased IL-1beta production."

26196303

➶

reach

"AMPKalpha activator AICAR (5-aminoimidazole-4-carbox-amide-1-beta-d-ribofuranoside) inhibited NLRP3 inflammasome activation and decreased IL-1beta release and restored impaired insulin signal pathway induced by palmitate."

31705915

➶

reach

"AICAR and salicylate inhibited NLRP3 induction and caspase-1 activation, and as a result, IL-1beta secretion was reduced."

26196303

INDRA sources:

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IndraLab

Statements

AICA ribonucleotide inhibits NLRP3. 3 / 3

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