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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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BAP1 decreases the amount of TERT. 3 / 3

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"In conclusion, the results from the present study provide evidence to suggest that BAP1 and possibly PARP-3 repress hTERT transcription within breast cancer cells, which supports the hypothesis that multiple sequences on human chromosome 3p may be responsible for regulating hTERT transcription."

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"Interestingly, literature data suggest that BAP1 could downregulate TERT expression (Linne et al., 2017)."

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"Chromosome 3p21.1-21.3 encoded sequences BAP1, but not SETD2 PARP-3 and PBRM1, repress hTERT transcription within 21NT cells."

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BAP1 decreases the amount of TERT. 3 / 3

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