IndraLab

Statements

CALM1 binds APP. 4 / 4
| 4
sparser
"Molecular simulation suggests that the appropriate size of CAM and the cavity of β-sheets facilitate the interaction between CAM and Aβ aggregates; additionally, the H-bonding-favored amino acid residues in the cavity provide a precondition for the interaction."
30345755
sparser
"Amyloid beta can bind to CAM (calcium binding protein and sensor) and participate in CAM-mediated events like acquisition and consolidation."
38211841
sparser
"APP interacts with neuronal-glial CAM (NgCAM), the chicken ortholog of L1, in the chick brain, and APP and sAPPα enhance NgCAM-dependent axon growth in retinal ganglion cells ( xref ) ( xref i)."
35959488
sparser
"CAM specifically interacts with Aβ aggregates but does not disturb the cerebral metal homeostasis and enzymatic systems."
30345755