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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BetA1 inhibits KCNMA1. 2 / 2

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"Beta 1 is preferentially expressed in the low-frequency-tuned distal HCs, and appears to slow BK channel kinetics XREF_BIBR - XREF_BIBR."

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"The beta1-to-beta2 mutations R11A and T14D in beta1 diminished the DeltaV 0.5 of the resulting Slo1 + beta1 complexes by PIP 2 from -45 mV to -27.9 +/- 3.6 mV (8) and -34.5 +/- 2.5 mV (11), respectively, which were indistinguishable from that observed in Slo1 + beta1 Delta2-32 (P = 0.80 and 0.09, respectively)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...