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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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YOD1 inhibits SQSTM1. 3 / 3

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"Hence, our data define that YOD1 antagonizes TRAF6 and p62 dependent IL-1 signaling to NF-kappaB."

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"YOD1 antagonizes ubiquitin ligase TRAF6 and p62 dependent interleukin-1 signaling to NF-kappaB."

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"Indeed, co-IP experiments using MYC-TRAF6 together with Crimson-p62 and GFP-YOD1 revealed that YOD1 was able to inhibit the association of TRAF6 and p62, while p62 did not alter the binding of YOD1 to TRAF6 (XREF_FIG)."

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YOD1 inhibits SQSTM1. 3 / 3

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