IndraLab

Statements

YOD1 inhibits SQSTM1. 3 / 3
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"Hence, our data define that YOD1 antagonizes TRAF6 and p62 dependent IL-1 signaling to NF-kappaB."
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"YOD1 antagonizes ubiquitin ligase TRAF6 and p62 dependent interleukin-1 signaling to NF-kappaB."
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"Indeed, co-IP experiments using MYC-TRAF6 together with Crimson-p62 and GFP-YOD1 revealed that YOD1 was able to inhibit the association of TRAF6 and p62, while p62 did not alter the binding of YOD1 to TRAF6 (XREF_FIG)."
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