IndraLab

Statements

PSMD14 inhibits IL1B. 4 / 4
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"As expected, ectopic POH1 expression also substantially inhibited IL-1beta secretion."
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"Collectively, these results indicate that POH1 in macrophages inhibits IL-1beta activation upon inflammasome activation."
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"Consistently, POH1 overexpression greatly inhibited IL-1beta secretion in LPS primed cells upon stimulation of ATP, nigericin, poly (dA : dT), flagellin, whereas no significant differences were found in the production of IL-6 or TNFalpha in these BMDMs (Figs."
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"POH1 negatively regulates IL-1beta production."
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