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C1QTNF9 increases the amount of USP22. 4 / 4
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"We found that CTRP9 increased the expression of USP22, which triggered the de-ubiquitination of Sirt1 and promoted cell autophagy.In conclusion, the present study demonstrated that CTRP9 alleviated li[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"As illustrated, both mRNA and protein expression of USP22 were upregulated by CTRP9 treatment in a dose-dependent manner ( Fig. 3 A&3B)."
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"However, the relationship between CTRP9 and Sirt1 has not been fully explored in AS progression.In the present study, we demonstrated that CTRP9 upregulated the expression of USP22, a kind of deubiqui[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Collectively, these results revealed that CTRP9 promoted USP22 expression, which removed the conjugated poly-ubiquitin chains from Sirt1 and enhanced the stabilization of Sirt1 protein.As shown in Fig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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