IndraLab

Statements

TNF activates UCHL1. 4 / 5
| 4
reach
"Presumably, TNFalpha is able to up-regulate UCH-L1 protein levels in RASMCs that UCH-L1 gene translation is blocked by cycloheximine if TNFalpha inhibits UCH-L1 degradation."
19945429
reach
"These results indicate that TNFalpha up-regulates UCH-L1 via a translational regulation."
19945429
reach
"These results suggest that TNFalpha up-regulates UCH-L1 protein via a posttranscriptional regulation in VSMCs."
19945429
reach
"Overall, our data demonstrate that TNFalpha up-regulates UCH-L1 via a translational regulation to inhibit ERK activity, thereby providing a negative feedback to control its growth promoting signaling in VSMCs."
19945429