IndraLab

Statements

BRCC3 deubiquitinates Interferon. 3 / 3
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reach
"Dr. Greenberg group from University of Pennsylvania showed that BRCC36 containing deubiquitinating complex BRISC which is also a sister protein complex of nuclear RAP80-BRCA1 complex, deubiquitinates type I interferon receptor (IFNAR1), resulting in its delayed lysosomal dependent degradation."
27211605
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"In the BRCC36 isopeptidase complex, BRCC36 promotes interferon dependent responses by deubiquitinating and stabilizing the type I interferon receptor XREF_BIBR."
27774986
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"The Abraxas complex (ARISC) functions in DNA repair and breast cancer suppression, while the BRCC36 isopeptidase complex (BRISC) promotes interferon dependent responses by deubiquitinating and stabilizing the type I interferon receptor, IFNAR1."
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