IndraLab

Statements

Testosterone inhibits KCNH2. 4 / 4
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"[Testosterone modulation of HERG potassium channel blockade induced by neuroleptics]."
11519244
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"Given that testosterone can downregulate HERG channels, we examined whether it may also modify the channel sensitivity to neuroleptics."
11377395
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"Here by using neuroleptic agents haloperidol, pimozide, and fluspirilene, all of which can induce TdP, and a steroid hormone sensitive system Xenopus oocytes for HERG channels expression we show that testosterone is able to reduce HERG blocking potency of neuroleptics."
11377395
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"Testosterone mediated modulation of HERG blockade by proarrhythmic agents."
11377395