IndraLab

Statements


NOX4 activates UCHL1. 3 / 3
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"Silencing NOX4, which generates H 2 O 2, with siRNA eliminated the effect of UCH-L1 on cell migration."

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"The amount of NOX4 protein expressed in B16F10 cells overexpressing UCH-L1 was also not significantly different from that in B16F10 cells in which UCH-L1 was knocked down (XREF_SUPPLEMENTARY)."

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"UCH-L1 induced active NOX4 by deubiquitination of NOX4, and then increased ROS which induce angiogenesis in HUVECs."