IndraLab

Statements


| 2

reach
"Preliminary results indicate that the hERG blocker E-4031 can stimulate irregular, arrhythmic beating patterns in the cardiomyocytes from both species, and that immediate subsequent treatment with the hERG enhancer nicorandil can rescue these back to regular beating patterns, similar to those observed when the cells were untreated."

reach
"All tested concentrations of BIC K and nicorandil exhibited APD90 shortening in guinea pig hearts ( Fig. 4 c), indicating their potential in treating E4031-induced LQT2."