IndraLab

Statements


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"In addition, USP10 stimulates the transport of multiple p62-positive ubiquitinated protein aggregates to the perinuclear region to form one big aggregate (aggresome)."

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"These results suggested that USP10 functions to stimulate transport of p62 aggregates to the perinuclear aggresome formation site."

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"USP10, by interacting with p62, further augments p62-induced ubiquitinated protein aggregation and then stimulates the transport of p62/ubiquitinated protein aggregates to the perinuclear aggresome-forming site."