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CLK3 activates USP13. 2 / 3
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"Moreover, CLK3 specifically has been shown to activate the ubiquitin-specific peptidase 13 (USP13) through phosphorylation [66], and although they did not further investigate it, coIP-MS experiments published by Funnel et al. showed that the protein most significantly associated with CLK2 was no splicing factor, but USP7 [49]."
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"XREF_FIG indicates that CLK3 knockdown in HuCCT1 cells strongly impaired the interaction of USP13 with c-Myc."
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