IndraLab

Statements


Modified BAP1 increases the amount of PPARGC1A. 2 / 2
| 2

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"In line with our observation that BAP1 is a deubiquitinase for PGC-1alpha in vitro, hepatic BAP1 overexpression increases the protein level of PGC-1alpha (XREF_FIG)."

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"Overexpression of BAP1 does not increase global ubiquitination, but substantially increases the level of PGC-1alpha and decreases PGC-1alpha ubiquitination as normalized to the protein level (XREF_FIG)."