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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified BAP1 increases the amount of PPARGC1A. 2 / 2

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"In line with our observation that BAP1 is a deubiquitinase for PGC-1alpha in vitro, hepatic BAP1 overexpression increases the protein level of PGC-1alpha (XREF_FIG)."

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"Overexpression of BAP1 does not increase global ubiquitination, but substantially increases the level of PGC-1alpha and decreases PGC-1alpha ubiquitination as normalized to the protein level (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...