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COPS6 decreases the amount of FOXO4. 3 / 3
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"In contrast, protein analysis demonstrated that CSN6 knockdown reduced the expression of Glut1 while increased the expression of FOXO4 (Figure 5F)."
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"In line with this finding, Western blotting showed that knockdown of CSN6 by shRNA increased the steady‐state expression of FOXO4 (Figure 1F)."
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"We then found that CSN6 decreased the steady‐state expression of FOXO4 in a dose‐dependent manner in several CRC cell lines (Figure 1E, Figure S2A, Supporting Information)."
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