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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

DDX58 bound to NOP53 activates USP15. 1 / 1

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"These results taken together indicated that GLTSCR2 interacted with RIG-I and USP15 in a complex to support the activity of USP15 to remove K63 linked polyubiquitin chains from RIG-I, leading to inactivation of RIG-I and blockage of IFN-beta induction."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...