IndraLab

Statements

OSM activates PTK2B. 2 / 2
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sparser
"These results suggest that, in marrow endothelium, activation of RAFTK by VEGF, VRP, OSM, and bFGF represents a new element in the signal transduction pathways used by these growth factors and likely acts to coordinate signaling from their surface receptors to the cytoskeleton, thereby modulating cell growth and function."
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reach
"Further studies also suggest that in KS, OSM and bFGF induce RAFTK, a focal adhesion kinase downstream of JNK, which acts as a convergence site for intracytoplasmic kinases and adapter molecules and increase cytokine signaling cascades and promoting cell growth (210)."
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