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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified CYLD decreases the amount of CXCL8. 2 / 2

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"As shown in XREF_FIG, DUB activity deficient CYLD mutant (CYLD H/N) had no effect on NTHi induced MKP-1 and IL-8 expression, whereas overexpression of CYLD WT enhanced MKP-1 induction and suppressed IL-8 expression."

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"Moreover, overexpression of CYLD WT suppressed, whereas CYLD knockdown by siCYLD enhanced, MEK-CA-induced IL-8 expression (XREF_FIG and XREF_SUPPLEMENTARY)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...