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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP13 activates E3_Ub_ligase. 2 / 2

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"Thus, several ubiquitin-conjugating E2 enzymes (UBE2L3, UBE2L5), the E3 ubiquitin ligases (TRIM21, TRIM38, ARIH2) and the ubiquitin specific protease or deconjugases (USP13) are 1.5-3.2-fold induced in the infected cells, while other E2, E3 enzymes and deconjugases (e.g."

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"In melanoma cells, USP13 attenuates the autodegradation of Siah2, a RING (really interesting new gene) finger family E3 ubiquitin ligase."

27923907

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...