
IndraLab
Statements
reach
"89 Thus, we hypothesize that loss of cacna1c resulting in deficient Ca v 1.2 signaling may inhibit Akt that subsequently (1) suppresses phosphorylation of TSC1/2 and increases its inhibitory effect on mTORC1 phosphorylation, and separately (2) activates PERK and induces eIF2alpha phosphorylation."