IndraLab

Statements


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"This mechanism not only positions OTUD3 at the nexus of iron metabolism and cell survival but also highlights the OTUD3-SLC7A11 axis as a promising therapeutic target for overcoming drug resistance in ccRCC."

sparser
"This OTUD3-SLC7A11 axis enhances cystine uptake, facilitates glutathione synthesis, and suppresses deleterious lipid peroxidation, ultimately inhibiting ferroptosis [ xref ]."