IndraLab

Statements

reach
"Whereas MG-132 can also inhibit cathepsin B and calpains, the fact that both lactacystin and PS341 had similar effects strongly suggests that the proteasome is responsible for the modification of 4E-BP1 in our system."
18021075
reach
"It needs to be further studied how not lipidated BmAtg8 is localized to membranes and then lipidated, which is also not fully understood in other species.By in vitro assays, MG132 represses proteolyti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27693582
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"Surprisingly, MG132 also blocked cathepsin B, and at concentrations that were even lower than those required for blocking cathepsin C (XREF_FIG), indicating that MG132 blocks a wide range of proteases."
24893007
sparser
"Whereas MG-132 can also inhibit cathepsin B and calpains, the fact that both lactacystin and PS341 had similar effects strongly suggests that the proteasome is responsible for the modification of 4E-BP1 in our system."
18021075
reach
"We found that MG132 caused an 80% inhibition of Cathepsin B, whereas lactacystin only slightly (< 10%) inhibited Cathepsin B. Therefore, the strong inhibitory effect of MG132 on degradation of EGF can be explained by the inhibitory effect of MG132 on Cathepsin B."
11864992