IndraLab

Statements


KCNMA1 activates NADase. 2 / 2
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"These and subsequent studies provided evidence that SLO mediated delivery of NADase augmented the cytotoxic effect of SLO and induced epithelial cell apoptosis [XREF_BIBR, XREF_BIBR]."

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"Whereas NADase delivery to epithelial cells is mediated by SLO secreted from GAS bound to the cell surface, in macrophages, the source of SLO and NADase is GAS contained within phagolysosomes."