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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified USP46 increases the amount of PHLPP1. 1 / 1

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"When a low concentration of PHLPP1 plasmid was transfected into cells alone, the level of PHLPP1 was not sufficient to significantly reduce the rate of cell proliferation, whereas co-expression of USP46 allowed the expression of PHLPP1 to surpass the threshold needed to induce the significant effect (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...