IndraLab

Statements


KB-R7943 inhibits KCNH2. 3 / 3
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"This study investigated KB-R7943 inhibition of hERG (human ether-a-go-go-related gene) K (+) channels that underpin the cardiac rapid delayed rectifier potassium current, I (Kr)."

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"High potency inhibition of hERG potassium channels by the sodium-calcium exchange inhibitor KB-R7943."

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"For example, KB-R7943, a widely used I NCX inhibitor, was found to inhibit the hERG channel 32 and L-type Ca 2+ channels 33 with a similar potency as I NCX antagonist actions."