IndraLab

Statements

USP33 activates laminin. 4 / 4
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"These findings are the first to describe that USP33 promoted laminin-dependent cell migration by stabilizing integrin α6, which provides an insight into the mechanistic roles of USP33-integrin α6 axis in ESCC metastasis."
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"We found that integrin α6 and USP33 overexpression in USP33-knockdown cells can largely rescue cell migration abilities on laminin in both KYSE-150 and KYSE-450 cells compared to indicated knockdown cells (Fig. 5C), which highlights the importance of integrin α6 in USP33-mediated ESCC cell migration on laminin."
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"USP33 promotes laminin-dependent cell adhesion and migration."
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"USP33 promoted laminin-dependent adhesion, spreading, and migration of ESCC cells but not their proliferation."
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