IndraLab

Statements

reach
"USP15 promotes the apoptosis of degenerative nucleus pulposus cells by suppressing the PI3K and AKT signalling pathway."
33135363
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"Under these standard T cell differentiation conditions, USP15 deficient and wild-type T cells were similar in differentiation and proliferation, although the USP15 deficient T cells had moderately enhanced apoptosis compared to wild-type T cells (XREF_SUPPLEMENTARY)."
24777531
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"The findings that USP15 deficiency promotes T cell activation and cancer cell apoptosis indicated that inhibition of USP15 might suppress tumor growth both via a tumor cell-intrinsic mechanism and by enhancing the anti-tumor host defense."
24777531
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"It was shown that when the XIAP gene was expressed in rat neonatal cardiomyocytes, it attenuated apoptosis induced by protein kinase C inhibition, hypoxia/ischemia, or isoproterenol stimulation.Ubiquitin-specific protease 15 (USP15), a member of cysteine protease deubiquitinases."
32708358
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"Crucially, ectopic expression of either p53 R175H or USP15 promoted p53 triggered apoptosis in human cervical cancer cells."
31749782