IndraLab

Statements


USP15 decreases the amount of RAF1. 3 / 4
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"Concordantly, depletion of USP15 in these cells caused a reduction of CRAF expression levels but did not affect the MEK or ERK phosphorylation status (XREF_FIG C)."

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"RT-PCR analysis of mRNA levels showed that USP15 depletion with two independent oligos causes a reduction of CRAF transcript levels (XREF_FIG A)."

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"Although, USP15 depletion reduced the level of C-RAF, it had no effect on the level of B-RAF and p-MEK in B-RAFV600E harbouring melanoma cells [155]."