IndraLab

Statements


USP7 leads to the deubiquitination of RING1. 2 / 2
| 2

reach
"the ubiquitin C-terminal hydrolase ubiquitin-specific protease 7 [USP7] that prevents self-ubiquitination of RING1 and PCGF to stabilize the complex and thus regulates H2A monoubiquitination levels [de Bie et al., 2010; Maertens et al., 2010; Hu et al., 2014; Maat et al., 2021]) (Figure 1)."

reach
"His ubiquitin pull-down analysis showed that HSCARG and USP7 inhibited RING1 ubiquitination in a synergy manner."