IndraLab

Statements



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"Depletion of USP37 also reduced cellular proliferation and led to increased sensitivity to agents that induce replication stress."

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"USP37 promotes cell proliferation by stabilizing 14-3-3gamma."

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"XREF_BIBR Therefore, it is possible that IH mediated miR-320b reduction in lung cancer cells resulted in the upregulation of USP37, which further promoted cancer cell proliferation, invasion, and survival."

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"We found that lower expression level of USP37 obviously impaired the expression of Hh targets (Smo and Gli-1) and cell proliferation marker Ki-67 in the tumor tissues as seen by immunohistochemical staining (Fig. 8e)."

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"Knockdown of USP37 inhibits cell proliferation and induces apoptosis To investigate the latent role of USP37 gene in the transformation of breast cancer cells , cell proliferation was examined by CCK-8 assay ."

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"Accumulating evidence has demonstrated that USP37 promotes lung cancer cell proliferation, migration, and invasion XREF_BIBR but inhibits lung cancer cell apoptosis in a deubiquitination dependent manner."

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"Notably, our results showed that overexpression of USP37, but not USP37 (C350S), enhanced the proliferation of cancer cells when 14-3-3gamma was co-transfected."

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"On the other hand, USP37 shRNAs inhibited the proliferation of keloid fibroblasts with diminished c-Myc and Collagen I expression."