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Statements

TSC1 binds TSC2, AMPK, and MTOR. 2 / 2

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"Sestrins inhibit mTORC1 activity by interacting with mTOR pathway suppressors AMPK, TSC1, and TSC2 [ xref ]."

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"The complex of hamartin (TSC1) and tuberin (TSC2) interact with AMPK and mTOR, and mutations in TSC1 or TSC2 lead to uncontrolled cell growth. xref TSC is associated with characteristic neoplasms such as neurofibromas in the skin, angiomyolipoma in the kidney and LAM in the lung."

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IndraLab

Statements

TSC1 binds TSC2, AMPK, and MTOR. 2 / 2

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