IndraLab

Statements

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"XREF_BIBR, XREF_BIBR Furthermore, deubiquitylating enzyme USP15 mediates K48 linked deubiquitylation of ALK3, to promote ALK3-smad1 signal and BMP induced osteoblast differentiation."
27563484
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"USP15 stimulates RORgammat activity and Th17 differentiation by enhancing SRC1 recruitment."
27430721
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"Reduction of USP15 expression from C2C12 myoblast cells inhibited BMP induced osteoblastic differentiation, as judged by the reduction in alkaline phosphatase induction."
24850914
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"Loss of USP15 in mouse myoblast cells suppressed BMP induced osteoblast differentiation."
27155333
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"USP15 deficiency promotes the activation of naive CD4 + T cells and their subsequent differentiation into the IFN-gamma-producing Th1 cells."
26686633
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"The mutation of Lys 446 to Arg or the deubiquitination of Lys 446 by USP15 promotes NCOA1 recruitment and Th17 differentiation."
31386594
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"We also show that loss of USP15 expression from mouse myoblast cells inhibits BMP induced osteoblast differentiation."
24850914
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"We previously revealed that USP15 promotes Th17 differentiation through removing a ubiquitin chain conjugated to Lys446 of RORγt which prevents the recruitment of SRC1 ."
34135062