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CNR1 binds PKMYT1, DNMT1, EZH2, and KCNA1. 1 / 1

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"EZH2 is essential for DNMTs to bind to the EZH2-target promoters such as MYT1 , KCNA1 and cannabinoid receptor 1 ( CNR1 ), and silences expression of these genes. xref Imatinib increased levels of both EZH2 and DNMT3A in leukemia cells ( xref ), which probably caused global epigenetic aberrations and downregulated the expression of important genes involved in regulation of cell growth, apoptosis and drug metabolism, which could relate to acquisition of drug resistance."

22829096

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IndraLab

Statements

CNR1 binds PKMYT1, DNMT1, EZH2, and KCNA1. 1 / 1

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