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COPS5 activates ERBB2. 2 / 2

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"Through Inhibition of HER-2 by herceptin, Jab1 and COPS5 expression was attenuated in various breast cancer cell lines."

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"Furthermore, two ErbB2 downstream signaling proteins [phosphatidylinositol 3 (PI3) kinase and protein kinase B (AKT)] were also activated by Jab1 overexpression in these cells."

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IndraLab

Statements

COPS5 activates ERBB2. 2 / 2

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