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Statements


COPS6 inhibits turnover OCT1. 2 / 2
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eidos
"c In DLD-1 cells expressing scrambled or CSN6-specific shRNA , CSN6 knockdown reduced the turnover rate of the TRIM21 protein and increased the turnover rate of OCT1 ."

eidos
"Indeed , CSN6 knockdown led to decelerated turnover of TRIM21 but accelerated turnover of OCT1 ( Fig. 4c ) ."