IndraLab

Statements

BAP1 inhibits ERK. 4 / 4
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"Taken together, our data suggested that BAP1 negatively regulated the ERK1/2 and JNK/c-Jun signaling pathways to exert its tumor-suppressive functions in ICC."
30305612
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"All of these results further confirmed that BAP1 suppressed ICC cell proliferation, cell cycle progression, and invasion via inhibiting ERK1/2 and JNK/c-Jun signaling pathways."
30305612
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"The observed inverse relationship between BAP1 expression and ERK1/2 polyubiquitination suggests that BAP1 inhibits the ERK signaling pathway by deubiquitinating the K63-linked polyubiquitin of ERK1/2."
37964637
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"BAP1 restricted the growth cycle of intrahepatic cholangiocarcinoma by regulating ERK1/2 and JNK/c-Jun axis (Chen et al. 2018)."
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