IndraLab

Statements

AKT phosphorylates COPS6. 7 / 7
| 3 2 2
sparser
"As for the phosphorylation event, Akt can phosphorylate CSN6 and MDM2."
24286178
rlimsp
"For instance, Akt can positively regulate CSN6 by phosphorylation."
24286178
sparser
"During EGF stimulation, CSN6 is phosphorylated by protein kinase B. This rescues CSN6 from ubiquitinylation and degradation [ 43 ] and induces a stabilization of the CRL4 substrate receptor COP1, whic[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36041947
reach
"As for the phosphorylation event, Akt can phosphorylate CSN6 and MDM2."
24286178
reach
"To determine whether the PKB/Akt‐mediated CSN6 phosphorylation affects FOXO4 stability, we examined the steady‐state expression of FOXO4 and COP1 in the presence of CSN6S60A, a construct with no PKB/Akt phosphorylation site."
33101846
reach
"These results indicate that PKB/Akt‐mediated CSN6 phosphorylation is critical in stabilizing COP1, thereby enhancing ubiquitination level of FOXO4."
33101846
rlimsp
"As for the phosphorylation event, Akt can phosphorylate CSN6 and MDM2."
24286178