IndraLab

Statements

CYLD leads to the deubiquitination of DVL. 3 / 3
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"Knockout of CYLD in tumor cells can prevent K63 linked deubiquitination of Dvl [Dishevelled], which enhances Wnt and beta-catenin signaling [XREF_BIBR]."
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"It is also reported that a tumor suppressor CYLD deubiquitinase inhibits the ubiquitination of Dvl."
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"Based on the established role of Wnt signaling in self-renewal of the skin, associated cell lineage decisions, and skin appendage formation (Fuchs, 2007), we propose that increased or prolonged activa[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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