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Nicotine inhibits OTUD3. 2 / 2

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"Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer."

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"Here we show that OTU domain-containing protein 3 ( OTUD3 ) is downregulated by nicotine and correlates with poor prognosis in heavy-smoking esophageal cancer patients ."

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Nicotine inhibits OTUD3. 2 / 2

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