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Chloroquine inhibits MYD88. 2 / 2

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"Chloroquine (CQ) has been shown to affect LPS-TLR4 colocalization and inhibit both MyD88 dependent and TRAM and TRIF dependent pathways, though the mechanism involved is still poorly understood."

28134560

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"Chloroquine, an inhibitor of CpG triggered cytokine secretion, blocked TLR9 and MyD88 dependent cytokine secretion as expected but failed to inhibit CpG induced Src family kinase activation and its dependent cellular responses."

16567503

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IndraLab

Statements

Chloroquine inhibits MYD88. 2 / 2

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